Biomedical Instrumentation

(3-0-0-3)

CMPE Degree: This course is Elective for the CMPE degree.

EE Degree: This course is Elective for the EE degree.

Lab Hours: 0 supervised lab hours and 0 unsupervised lab hours.

Technical Interest Group(s) / Course Type(s): Bioengineering, Courses for non-ECE majors, Cross-listed courses

Course Coordinator: Omer T Inan

Prerequisites: ECE 3030 [min C] or ECE 3040 [min C] or ECE 3710 [min C] or ECE3043 [min C]

Corequisites: None.

Catalog Description

A study of physiological sensing topics from a systems viewpoint. Pertinent physiological and electro-physiological concepts will be covered. Crosslisted with CHE and ME 4781

Textbook(s)

Medical Instrumentation: Application and Design

Course Outcomes

  1. Analyze op amp based circuits and systems for biomedical sensing
  2. Describe challenges in real-world biomedical sensing problems such as motion artifacts, skin-electrode interface, and low signal to noise ratio
  3. Develop strategies for mitigating these real-world challenges including through the design of multi-modal sensing systems and high performance circuit design
  4. Design biomedical sensing systems based on discrete analog and embedded systems hardware
  5. Communicate the design of biomedical sensing systems to a diverse audience of engineers and / or clinicians via written and oral presentation

Student Outcomes

In the parentheses for each Student Outcome:
"P" for primary indicates the outcome is a major focus of the entire course.
“M” for moderate indicates the outcome is the focus of at least one component of the course, but not majority of course material.
“LN” for “little to none” indicates that the course does not contribute significantly to this outcome.

1. ( P ) An ability to identify, formulate, and solve complex engineering problems by applying principles of engineering, science, and mathematics

2. ( P ) An ability to apply engineering design to produce solutions that meet specified needs with consideration of public health, safety, and welfare, as well as global, cultural, social, environmental, and economic factors

3. ( P ) An ability to communicate effectively with a range of audiences

4. ( LN ) An ability to recognize ethical and professional responsibilities in engineering situations and make informed judgments, which must consider the impact of engineering solutions in global, economic, environmental, and societal contexts

5. ( M ) An ability to function effectively on a team whose members together provide leadership, create a collaborative and inclusive environment, establish goals, plan tasks, and meet objectives

6. ( P ) An ability to develop and conduct appropriate experimentation, analyze and interpret data, and use engineering judgment to draw conclusions

7. ( LN ) An ability to acquire and apply new knowledge as needed, using appropriate learning strategies.

Strategic Performance Indicators (SPIs)

Not Applicable

Course Objectives

Topical Outline

(5 hours) Basic Concepts of Instrumentation
Static and dynamic characteristics
Design criteria
Instrumentation Amplifiers

(5 hours) Membrane Biophysics
Diffusion across cell membranes
Nernst potentials
Diffusion potentials
Goldman equation

(6 hours) Action Potentials
Membrane behavior
Origin of action potential
Hodgkin-Huxley equations
Modeling
Propagation of action potentials
Subthreshold stimuli

(4 hours) Biopotential Electrodes
Fundamentals
Body surface electrodes
Microelectrodes

(5 hours) Electrophysiology of the Heart
Anatomy/physiology of heart
Body surface potentials
Electrocardiogram
Heart vector
Standard leads

(6 hours) Electrophysiology of Neuromuscular System
Neuromuscular Junction
Transmitters
Poisson statistics for transmitters
Postjunctional response
Anatomy/physiology of muscle
Myofibrils and filaments
Excitation contraction
Electromyography
Functional neuromuscular stimulation

(3 hours) Miscellaneous Electrophysiology
Electroencephalography
Electroretinogram

(5 hours) Biomedical Transducers
Displacement transducers
Thermocouples and thermistors

(4 hours) Measurement of Blood and Gas Flows
Electromagnetic flowmeter
Ultrasonic flowmeter
Thermodilution catheter

(2 hours) Exams