Biomedical Applications of Microelectromechanical Systems

(3-0-0-3)

CMPE Degree: This course is Not Applicable for the CMPE degree.

EE Degree: This course is Not Applicable for the EE degree.

Lab Hours: 0 supervised lab hours and 0 unsupervised lab hours.

Technical Interest Group(s) / Course Type(s): Bioengineering

Course Coordinator:

Prerequisites: ECE 6450

Corequisites: None.

Catalog Description

MEMS processing technologies, design of fabrication process flows, and applications of the technologies to the development of biomedical micro instrumentation an detection methodologies.

Textbook(s)

Course Outcomes

Not Applicable

Student Outcomes

In the parentheses for each Student Outcome:
"P" for primary indicates the outcome is a major focus of the entire course.
“M” for moderate indicates the outcome is the focus of at least one component of the course, but not majority of course material.
“LN” for “little to none” indicates that the course does not contribute significantly to this outcome.

1. ( Not Applicable ) An ability to identify, formulate, and solve complex engineering problems by applying principles of engineering, science, and mathematics

2. ( Not Applicable ) An ability to apply engineering design to produce solutions that meet specified needs with consideration of public health, safety, and welfare, as well as global, cultural, social, environmental, and economic factors

3. ( Not Applicable ) An ability to communicate effectively with a range of audiences

4. ( Not Applicable ) An ability to recognize ethical and professional responsibilities in engineering situations and make informed judgments, which must consider the impact of engineering solutions in global, economic, environmental, and societal contexts

5. ( Not Applicable ) An ability to function effectively on a team whose members together provide leadership, create a collaborative and inclusive environment, establish goals, plan tasks, and meet objectives

6. ( Not Applicable ) An ability to develop and conduct appropriate experimentation, analyze and interpret data, and use engineering judgment to draw conclusions

7. ( Not Applicable ) An ability to acquire and apply new knowledge as needed, using appropriate learning strategies.

Strategic Performance Indicators (SPIs)

Outcome 1 (Students will demonstrate expertise in a subfield of study chosen from the fields of electrical engineering or computer engineering):
1. Design systems that probe biological processes using microelectromechanical
systems (MEMS).
2. Demonstrate working knowledge of the principles of operation and the
compatibility with biological material of various types of MEMS
3. Critically analyze an application of MEMS in solving a problem in biomedicine

Outcome 2 (Students will demonstrate the ability to identify and formulate advanced problems and apply knowledge of mathematics and science to solve those problems):
1. Quantitatively model and design microfluidic systems for analyzing biological materials at the cellular and molecular scales.

Outcome 3 (Students will demonstrate the ability to utilize current knowledge, technology, or techniques within their chosen subfield):
1. Read and communicate results from BioMEMS publications from archival research journals and conference proceedings.

Course Objectives

Topical Outline

Introduction to MEMS Devices and Applications, Biomedical Applications of MEMS

Materials & Biocompatibility

MEMS Fabrication Technologies
* Design of MEMS Fabrication Processes
* Driving Forces for Biomedical Relevant Actuators and Geometrical
* Scaling Effects

Sensing Mechanisms for Biosensors and Geometrical Scaling Effects

Microfluidic Systems Design
* Micropumps
* Microvalves
* Flow Rate Sensors
* Integrated Fluid Mixers

DNA Analysis Systems PCR, Electrophoresis and Arrays

DNA-based Sensors

Sample Pretreatment Systems, Integrated Sample Manipulation

Cellular Analysis Systems

Nano-Particle Separation Systems

Neural Stimulation and Recording Arrays

Bead based Biosensors, Magnetic Sensors for Biomedical Applications

Magnetics & Microfluidics

Cantilever based Biosensors

Chemical Sensors

Immunoassays

Technical Presentations